Ce cours a été conçu par Sophie Gilbert, Francis Desmeules et Vincent Gauvin et révisé par Pierre Baril le mardi 16 janvier 2024.

Bibliographie

Prehospital Tranexamic Acid for Severe Trauma.
PATCH-Trauma Investigators and the ANZICS Clinical Trials Group,Gruen RL,Mitra B,Bernard SA,McArthur CJ,Burns B,Gantner DC,Maegele M,Cameron PA,Dicker B,Forbes AB,Hurford S,Martin CA,Mazur SM,Medcalf RL,Murray LJ,Myles PS,Ng SJ,Pitt V,Rashford S,Reade MC,Swain AH,Trapani T,Young PJ, The New England journal of medicine 2023 Jul 13 389(2) 127-136

Protocol for a multicentre prehospital randomised controlled trial investigating tranexamic acid in severe trauma: the PATCH-Trauma trial.
Mitra B,Bernard S,Gantner D,Burns B,Reade MC,Murray L,Trapani T,Pitt V,McArthur C,Forbes A,Maegele M,Gruen RL,PATCH-Trauma study investigators,PATCH-Trauma Study investigators, BMJ open 2021 Mar 15 11(3) e046522

Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
CRASH-2 trial collaborators,Shakur H,Roberts I,Bautista R,Caballero J,Coats T,Dewan Y,El-Sayed H,Gogichaishvili T,Gupta S,Herrera J,Hunt B,Iribhogbe P,Izurieta M,Khamis H,Komolafe E,Marrero MA,Mejía-Mantilla J,Miranda J,Morales C,Olaomi O,Olldashi F,Perel P,Peto R,Ramana PV,Ravi RR,Yutthakasemsunt S, Lancet (London, England) 2010 Jul 3 376(9734) 23-32

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial.
CRASH-3 trial collaborators, Lancet (London, England) 2019 Nov 9 394(10210) 1713-1723

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial.
WOMAN Trial Collaborators, Lancet (London, England) 2017 May 27 389(10084) 2105-2116